Saccharomyces cerevisiae (R64-1-1)
Description

E3 ubiquitin ligase and putative helicase; involved in synthesis-dependent strand annealing-mediated homologous recombination; ensures precise end-joining along with Srs2p in the Yku70p/Yku80p/Lig4p-dependent nonhomologous end joining (NHEJ) pathway; localizes to both the mitochondrion and the nucleus; contains a Snf2/Swi2 family ATPase/helicase and a RING finger domain; interacts with Cdc48p and Smt3p; null mutant displays increased levels of spontaneous Rad52p foci [Source:SGD;Acc:S000004237]

Location

Chromosome XII: 628,684-633,354 reverse strand.

R64-1-1:BK006945.2

About this gene

This gene has 1 transcript (splice variant), 237 orthologues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
IRC20YLR247C_mRNA46711556aaYLR247C
 
Protein coding
Q06554 NM_001182134.1
NP_013348.1

Gene-based displays