Saccharomyces cerevisiae (R64-1-1)

Metalloendopeptidase of the mitochondrial inner membrane; important for adaptive responses to various homeostatic insults, preservation of normal mitochondrial function under damage-eliciting conditions, and stability of respiratory supercomplexes; involved in turnover of membrane-embedded proteins; mediates degradation of Cox1p in coa2 mutant cells; zebrafish ortholog has a role in organ development and mouse ortholog is also required for respiratory supercomplex stability [Source:SGD;Acc:S000001795]


Chromosome XI: 603,195-604,232 reverse strand.


About this gene

This gene has 1 transcript (splice variant) and 323 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P36163 -Ensembl Canonical