S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]

SLI2

Chromosome XI: 205,707-207,749 forward strand.

R64-1-1:BK006944.2

This gene has 1 transcript (splice variant), 390 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.

Show transcript tableHide transcript table