Saccharomyces cerevisiae (R64-1-1)
Description

S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]

Synonyms

SLI2

Location

Chromosome XI: 205,707-207,749 forward strand.

R64-1-1:BK006944.2

About this gene

This gene has 1 transcript (splice variant), 327 orthologues, 2 paralogues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
YPK1YKL126W_mRNA2043680aaYKL126W
 
Protein coding
P12688 NM_001179692.1
NP_012796.1

Gene-based displays