S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]
Chromosome XI: 205,707-207,749 forward strand.
This transcript has 1 exon, is annotated with 21 domains and features, is associated with 25 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YKL126W Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
YPK1 | YKL126W_mRNA | 2043 | 680aa | YKL126W | Protein coding | P12688 | - | Ensembl Canonical, |