Saccharomyces cerevisiae (R64-1-1)
Description

Histone H3-like centromere protein; associated with promoters, accessible chromatin, RNAPII-bound regions; phosphorylated Cse4p associates with centromeres; required for proper kinetochore function; levels regulated by E3 ubiquitin ligase Psh1p; phosphorylation may destabilize defective kinetochores to promote bi-orientation; ubiquitination of N-terminus regulates proteolysis for faithful chromosome segregation; yeast CSE4 can complement mutations in human homolog CENPA [Source:SGD;Acc:S000001532]

Synonyms

CSL2

Location

Chromosome XI: 346,075-346,764 reverse strand.

R64-1-1:BK006944.2

About this gene

This gene has 1 transcript (splice variant), 374 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
CSE4YKL049C_mRNA690229aaYKL049C
 
Protein coding
P36012 NM_001179615.1
NP_012875.2

Gene-based displays