Histone H3-like centromere protein; associated with promoters, accessible chromatin, RNAPII-bound regions; phosphorylated Cse4p associates with centromeres; required for proper kinetochore function; levels regulated by E3 ubiquitin ligase Psh1p; phosphorylation may destabilize defective kinetochores to promote bi-orientation; ubiquitination of N-terminus regulates proteolysis for faithful chromosome segregation; yeast CSE4 can complement mutations in human homolog CENPA [Source:SGD;Acc:S000001532]

Chromosome XI: 346,075-346,764 reverse strand.

This transcript has 1 exon, is annotated with 27 domains and features and is associated with 13 variant alleles.

This transcript is a product of gene YKL049C Show transcript tableHide transcript table