Saccharomyces cerevisiae (R64-1-1)
Description

Highly conserved zinc metalloprotease; functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; cleaves both isoprenylated and non-prenylated oligopeptides; contains multiple transmembrane spans; human homolog ZMPSTE24 implicated in mandibuloacral dysplasia (MAD), and can complement yeast null mutant [Source:SGD;Acc:S000003878]

Synonyms

AFC1, PIO2

Location

Chromosome X: 642,007-643,368 forward strand.

R64-1-1:BK006943.2

About this gene

This gene has 1 transcript (splice variant), 254 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
STE24YJR117W_mRNA1362453aaYJR117W
 
Protein coding
P47154 NM_001181775.1
NP_012651.1

Gene-based displays