Saccharomyces cerevisiae (R64-1-1)
Description

Cytosolic copper-zinc superoxide dismutase; detoxifies superoxide; stabilizes Yck1p and Yck2p kinases in glucose to repress respiration; phosphorylated by Dun1p, enters nucleus under oxidative stress to promote transcription of stress response genes; human ortholog SOD1 implicated in ALS complements a null allele; abundance increases under DNA replication stress and during exposure to boric acid; localization to mitochondrial intermembrane space is modulated by MICOS complex [Source:SGD;Acc:S000003865]

Synonyms

CRS4

Location

Chromosome X: 622,550-623,014 reverse strand.

R64-1-1:BK006943.2

About this gene

This gene has 1 transcript (splice variant), 286 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
SOD1YJR104C_mRNA465154aaYJR104C
 
Protein coding
P00445 NM_001181762.1
NP_012638.1

Gene-based displays