Cytosolic copper-zinc superoxide dismutase; detoxifies superoxide; stabilizes Yck1p and Yck2p kinases in glucose to repress respiration; phosphorylated by Dun1p, enters nucleus under oxidative stress to promote transcription of stress response genes; human ortholog SOD1 implicated in ALS complements a null allele; abundance increases under DNA replication stress and during exposure to boric acid; localization to mitochondrial intermembrane space is modulated by MICOS complex [Source:SGD;Acc:S000003865]
Chromosome X: 622,550-623,014 reverse strand.
This transcript has 1 exon, is annotated with 12 domains and features, is associated with 14 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YJR104C Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
SOD1 | YJR104C_mRNA | 465 | 154aa | YJR104C | Protein coding | P00445 | - | Ensembl Canonical, |