Saccharomyces cerevisiae (R64-1-1)
Description

Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p; contributes to GAP activity, inactivating Tem1 by stimulating GTP hydrolysis following damage or misalignment of the mitotic spindle; functions as a guanine-nucleotide exchange inhibitor (GDI) for Tem1p; involved in multiple cell cycle checkpoint pathways that control mitotic exit; required when telomeres are damaged, but not for all types of chromosomal DNA damage; phosphorylated by the Polo-like kinase Cdc5p [Source:SGD;Acc:S000003814]

Synonyms

IBD1

Location

Chromosome X: 534,027-535,751 forward strand.

R64-1-1:BK006943.2

About this gene

This gene has 1 transcript (splice variant), 25 orthologues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
BFA1YJR053W_mRNA1725574aaYJR053W
 
Protein coding
P47113 NM_001181711.3
NP_012587.3

Gene-based displays