Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p; contributes to GAP activity, inactivating Tem1 by stimulating GTP hydrolysis following damage or misalignment of the mitotic spindle; functions as a guanine-nucleotide exchange inhibitor (GDI) for Tem1p; involved in multiple cell cycle checkpoint pathways that control mitotic exit; required when telomeres are damaged, but not for all types of chromosomal DNA damage; phosphorylated by the Polo-like kinase Cdc5p [Source:SGD;Acc:S000003814]

Chromosome X: 534,027-535,751 forward strand.

This transcript has 1 exon, is annotated with 8 domains and features, is associated with 32 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YJR053W Show transcript tableHide transcript table