3'-5' DNA helicase involved in error-free bypass of DNA lesions; binds flap DNA, stimulates activity of Rad27p and Dna2p; prevents crossovers between ectopic sequences by removing substrates for Mus81-Mms4 or Rad1-Rad10 cleavage; homolog of human FANCM Fanconi anemia protein that is involved in stabilizing and remodeling blocked replication forks; member of SF2 DExD/H superfamily of helicases; nonsense or missense mutations in FANCM can make people more likely to get cancer [Source:SGD;Acc:S000001441]

Chromosome IX: 357,415-360,396 reverse strand.

R64-1-1:BK006942.2

This gene has 1 transcript (splice variant), 357 orthologues and is a member of 1 Ensembl protein family.

Show transcript tableHide transcript table