Nuclear envelope/ER integral membrane protein; interacts and functions with Brr6p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA export from the nucleus and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism [Source:SGD;Acc:S000001302]

Chromosome IX: 277,723-278,139 forward strand.

R64-1-1:BK006942.2

This gene has 1 transcript (splice variant) and 5 orthologues.

Show transcript tableHide transcript table