Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat; COPII coat is required for cargo selection during vesicle formation in ER to Golgi transport; scaffolding function of Lst1p required to generate vesicles that can accommodate difficult cargo proteins that include large oligomeric assemblies and asymmetrically distributed membrane proteins; homologous to Sec24p and Sfb2p [Source:SGD;Acc:S000001140]
LST1
Chromosome VIII: 299,145-301,934 reverse strand.
R64-1-1:BK006934.2
This gene has 1 transcript (splice variant), 393 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.