Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx1p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases under DNA replication stress; TRX2 has a paralog, TRX1, that arose from the whole genome duplication [Source:SGD;Acc:S000003441]
LMA1
Chromosome VII: 912,913-913,227 reverse strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 191 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
TRX2 | YGR209C_mRNA | 315 | 104aa | YGR209C | Protein coding | P22803 | - | Ensembl Canonical, |