Cystathionine beta-synthase; catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; advances passage through START by promoting cell growth which requires catalytic activity, and reducing critical cell size independent of catalytic activity; mutations in human ortholog CBS cause homocystinuria; human CBS can complement yeast null mutant [Source:SGD;Acc:S000003387]

NHS5, STR4, VMA41

Chromosome VII: 798,543-800,066 forward strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant), 367 orthologues and 6 paralogues.

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