Cystathionine beta-synthase; catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; advances passage through START by promoting cell growth which requires catalytic activity, and reducing critical cell size independent of catalytic activity; mutations in human ortholog CBS cause homocystinuria; human CBS can complement yeast null mutant [Source:SGD;Acc:S000003387]
Chromosome VII: 798,543-800,066 forward strand.
This transcript has 1 exon, is annotated with 25 domains and features, is associated with 33 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YGR155W Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
CYS4 | YGR155W_mRNA | 1524 | 507aa | YGR155W | Protein coding | P32582 | - | Ensembl Canonical, |