Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; ORM1 has a paralog, ORM2, that arose from the whole genome duplication [Source:SGD;Acc:S000003270]

Chromosome VII: 560,682-561,350 forward strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant), 281 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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