Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; ORM1 has a paralog, ORM2, that arose from the whole genome duplication [Source:SGD;Acc:S000003270]
Chromosome VII: 560,682-561,350 forward strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 337 orthologues and 1 paralogue.