Saccharomyces cerevisiae (R64-1-1)
Description

Coiled-coil protein involved in spindle-assembly checkpoint; required for inhibition of karyopherin/importin Pse1p (aka Kap121p) upon spindle assembly checkpoint arrest; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of anaphase promoting complex activity; forms a complex with Mad2p; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability [Source:SGD;Acc:S000003054]

Location

Chromosome VII: 347,119-349,368 forward strand.

R64-1-1:BK006941.2

About this gene

This gene has 1 transcript (splice variant), 321 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
MAD1YGL086W_mRNA2250749aaYGL086W
 
Protein coding
P40957 NM_001180951.3
NP_011429.3

Gene-based displays