Saccharomyces cerevisiae (R64-1-1)
Description

Transcription factor involved in iron utilization and homeostasis; binds consensus site PyPuCACCCPu and activates transcription in response to changes in iron availability; in iron-replete conditions localization is regulated by Grx3p, Grx4p, and Fra2p, and promoter binding is negatively regulated via Grx3p-Grx4p binding; AFT1 has a paralog, AFT2, that arose from the whole genome duplication; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003039]

Synonyms

RCS1

Location

Chromosome VII: 372,012-374,084 forward strand.

R64-1-1:BK006941.2

About this gene

This gene has 1 transcript (splice variant), 59 orthologues and 1 paralogue.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
AFT1YGL071W_mRNA2073690aaYGL071W
 
Protein coding
P22149 NM_001180936.1
NP_011444.1

Gene-based displays