Saccharomyces cerevisiae (R64-1-1)

Mannosyltransferase in the N-linked glycosylation pathway; catalyzes two consecutive steps in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol; human ALG2 complements the temperature sensitivity and dolichol-linked oligosaccharide biosynthesis defect of the alg2-1 mutant, but mutant form from a patient with CDG-Ii fails to complement [Source:SGD;Acc:S000003033]


Chromosome VII: 379,760-381,271 reverse strand.


About this gene

This gene has 1 transcript (splice variant), 346 orthologues and 4 paralogues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P43636 -Ensembl Canonical