ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003016]

CIM3, CRL3, SCB68, SUG1

Chromosome VII: 410,069-411,286 reverse strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant), 379 orthologues and 5 paralogues.

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