ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003016]
CIM3, CRL3, SCB68, SUG1
Chromosome VII: 410,069-411,286 reverse strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 377 orthologues and 5 paralogues.