E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex; catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA; phosphorylated; regulated by glucose; PDH complex is concentrated in spots within the mitochondrial matrix, often near the ERMES complex and near peroxisomes [Source:SGD;Acc:S000000980]
Chromosome V: 546,817-548,079 forward strand.
R64-1-1:BK006939.2
This gene has 1 transcript (splice variant), 388 orthologues and is a member of 1 Ensembl protein family.