Ubiquitin-specific protease involved in transport and osmotic response; negatively regulates Ras/PKA signaling; interacts with Bre5p to coregulate anterograde, retrograde transport between ER and Golgi; involved in transcription elongation in response to osmostress through phosphorylation at Ser695 by Hog1p; inhibitor of gene silencing; role in ribophagy; cleaves ubiquitin fusions but not polyubiquitin; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000953]

BLM3

Chromosome V: 469,686-472,424 reverse strand.

R64-1-1:BK006939.2

This gene has 1 transcript (splice variant), 353 orthologues and 15 paralogues.

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