ATP phosphoribosyltransferase; a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control [Source:SGD;Acc:S000000857]
Chromosome V: 264,892-265,785 reverse strand.
R64-1-1:BK006939.2
This gene has 1 transcript (splice variant), 341 orthologues and is a member of 2 Ensembl protein families.