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Saccharomyces cerevisiae (R64-1-1)
Description

Dimeric hypoxanthine-guanine phosphoribosyltransferase; catalyzes the transfer of the phosphoribosyl portion of 5-phosphoribosyl-alpha-1-pyrophosphate to a purine base (either guanine or hypoxanthine) to form pyrophosphate and a purine nucleotide (either guanosine monophosphate or inosine monophosphate); mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome [Source:SGD;Acc:S000002807]

Gene Synonyms

BRA6, HGPRTase, HPRT

Location

Chromosome IV: 1,270,068-1,270,733 forward strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 333 orthologues and 1 paralogue.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
HPT1YDR399W_mRNA666221aaYDR399W
 
Protein coding
Q04178 -Ensembl Canonical