Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence; protein abundance increases in response to DNA replication stress; mutations affecting Adk1p catalytic activity deregulate expression of phosphate utilization genes PHO5 and PHO84; human homolog AK1 can complement yeast adk1 mutant [Source:SGD;Acc:S000002634]

AKY1, AKY2

Chromosome IV: 916,486-917,154 forward strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 361 orthologues and 2 paralogues.

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