Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence; protein abundance increases in response to DNA replication stress; mutations affecting Adk1p catalytic activity deregulate expression of phosphate utilization genes PHO5 and PHO84; human homolog AK1 can complement yeast adk1 mutant [Source:SGD;Acc:S000002634]
AKY1, AKY2
Chromosome IV: 916,486-917,154 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 362 orthologues and 2 paralogues.