Ubiquitin-conjugating enzyme; key E2 partner with Ubc4p for the anaphase-promoting complex (APC); mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response; protein abundance increases in response to DNA replication stress key E2 partner with Ubc4p for the anaphase-promoting complex (APC) [Source:SGD;Acc:S000002584]

Chromosome IV: 816,878-817,525 forward strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 303 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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