Saccharomyces cerevisiae (R64-1-1)
Description

Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant [Source:SGD;Acc:S000002536]

Synonyms

ABP67

Location

Chromosome IV: 713,340-715,379 reverse strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 290 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
SAC6YDR129C_mRNA1929642aaYDR129C
 
Protein coding
P32599 NM_001180437.3
NP_010414.3

Gene-based displays