Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant [Source:SGD;Acc:S000002536]
Chromosome IV: 713,340-715,379 reverse strand.
This transcript has 2 exons, is annotated with 27 domains and features, is associated with 46 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YDR129C Show transcript tableHide transcript table
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