Saccharomyces cerevisiae (R64-1-1)
Description

DDK (Dbf4-dependent kinase) catalytic subunit; required for origin firing and replication fork progression in mitotic S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression; required for pre-meiotic DNA replication, meiotic DSB formation, recruitment of monopolin complex to kinetochores during meiosis I, regulation of meiosis-specific Ndt80p; mutation complemented by human CDC7 and DBF4 co-expression [Source:SGD;Acc:S000002175]

Synonyms

LSD6, SAS1

Location

Chromosome IV: 424,209-425,732 forward strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 268 orthologues, 2 paralogues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
CDC7YDL017W_mRNA1524507aaYDL017W
 
Protein coding
P06243 NM_001180076.3
NP_010267.3

Gene-based displays