DDK (Dbf4-dependent kinase) catalytic subunit; required for origin firing and replication fork progression in mitotic S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression; required for pre-meiotic DNA replication, meiotic DSB formation, recruitment of monopolin complex to kinetochores during meiosis I, regulation of meiosis-specific Ndt80p; mutation complemented by human CDC7 and DBF4 co-expression [Source:SGD;Acc:S000002175]

LSD6, SAS1

Chromosome IV: 424,209-425,732 forward strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 363 orthologues and 4 paralogues.

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