Saccharomyces cerevisiae (R64-1-1)

Component of the ESCRT-I complex; ESCRT-I is involved in ubiquitin-dependent sorting of proteins into the endosome; prevents polyubiquitination of the arrestin-related protein Rim8p, thereby directing its monoubiquitination by Rsp5p; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype; [Source:SGD;Acc:S000000514]

Gene Synonyms

VPL15, VPS23


Chromosome III: 105,696-106,853 reverse strand.


About this gene

This gene has 1 transcript (splice variant) and 326 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P25604 -Ensembl Canonical