Component of the ESCRT-I complex; ESCRT-I is involved in ubiquitin-dependent sorting of proteins into the endosome; prevents polyubiquitination of the arrestin-related protein Rim8p, thereby directing its monoubiquitination by Rsp5p; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype; [Source:SGD;Acc:S000000514]

Chromosome III: 105,696-106,853 reverse strand.

This transcript has 1 exon, is annotated with 14 domains and features, is associated with 24 variant alleles and maps to 46 oligo probes.

This transcript is a product of gene YCL008C Show transcript tableHide transcript table