Hexameric ring ATPase that remodels chromosome axis protein Hop1p; nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in rDNA; required for meiotic double-stranded break formation [Source:SGD;Acc:S000000390]
Chromosome II: 600,553-602,360 forward strand.
R64-1-1:BK006936.2
This gene has 1 transcript (splice variant), 31 orthologues and is a member of 1 Ensembl protein family.