Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres [Source:SGD;Acc:S000000340]

ESR1, RAD31, SAD3

Chromosome II: 505,668-512,774 forward strand.

R64-1-1:BK006936.2

This gene has 1 transcript (splice variant), 83 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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