Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase; electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm; protein abundance increases in response to DNA replication stress; human homolog ATP6V1B1, implicated in autosomal-recessive distal renal tubular acidosis (RTA) with sensorineural deafness, complements yeast null mutant [Source:SGD;Acc:S000000331]
ATPSV, VAT2
Chromosome II: 491,269-492,822 reverse strand.
R64-1-1:BK006936.2
This gene has 1 transcript (splice variant), 372 orthologues and 3 paralogues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
VMA2 | YBR127C_mRNA | 1554 | 517aa | YBR127C | Protein coding | P16140 | - | Ensembl Canonical, |