Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; GPB2 has a paralog, GPB1, that arose from the whole genome duplication [Source:SGD;Acc:S000000052]
KRH1
Chromosome I: 39,259-41,901 forward strand.
R64-1-1:BK006935.2
This gene has 1 transcript (splice variant), 17 orthologues and 1 paralogue.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
GPB2 | YAL056W_mRNA | 2643 | 880aa | YAL056W | Protein coding | P39717 | - | Ensembl Canonical, |