Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; GPB2 has a paralog, GPB1, that arose from the whole genome duplication [Source:SGD;Acc:S000000052]

KRH1

Chromosome I: 39,259-41,901 forward strand.

R64-1-1:BK006935.2

This gene has 1 transcript (splice variant), 16 orthologues and 1 paralogue.

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