Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; GPB2 has a paralog, GPB1, that arose from the whole genome duplication [Source:SGD;Acc:S000000052]
Chromosome I: 39,259-41,901 forward strand.
This transcript has 1 exon, is annotated with 7 domains and features, is associated with 85 variant alleles and maps to 23 oligo probes.
This transcript is a product of gene YAL056W Show transcript tableHide transcript table