DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase; involved in base excision repair; acts in both nucleus and mitochondrion; creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress; required for maintaining mitochondrial genome integrity; NTG1 has a paralog, NTG2, that arose from the whole genome duplication [Source:SGD;Acc:S000000013]
FUN33, ogg2, SCR1
Chromosome I: 126,903-128,102 reverse strand.
R64-1-1:BK006935.2
This gene has 1 transcript (splice variant), 369 orthologues and 1 paralogue.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
NTG1 | YAL015C_mRNA | 1200 | 399aa | YAL015C | Protein coding | P31378 | - | Ensembl Canonical, |