DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase; involved in base excision repair; acts in both nucleus and mitochondrion; creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress; required for maintaining mitochondrial genome integrity; NTG1 has a paralog, NTG2, that arose from the whole genome duplication [Source:SGD;Acc:S000000013]

Chromosome I: 126,903-128,102 reverse strand.

This transcript has 1 exon, is annotated with 11 domains and features, is associated with 37 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YAL015C Show transcript tableHide transcript table