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Saccharomyces cerevisiae (R64-1-1)
Description

Alpha-1,2-specific exomannosidase of the endoplasmic reticulum; involved in glycan trimming of both folded and misfolded glycoproteins; complexes with Pdi1p, and trims a mannose from Man8GlcNac2 glycans to generate Man7GlcNac2, an oligosaccharide signal on glycoproteins destined for ER-associated protein degradation; requires Pdi1p for stability and substrate recognition; human homolog EDEM1 can complement yeast null mutant [Source:SGD;Acc:S000001247]

Location
About this transcript

This transcript has 1 exon, is annotated with 26 domains and features and is associated with 48 variant alleles.

Gene

This transcript is a product of gene YHR204W Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
MNL1YHR204W_mRNA2391796aaYHR204W
 
Protein coding
P38888 -Ensembl Canonical
Statistics

Exons: 1, Coding exons: 1, Transcript length: 2,391 bps, Translation length: 796 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P38888

Version

YHR204W_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD