Alpha-1,2-specific exomannosidase of the endoplasmic reticulum; involved in glycan trimming of both folded and misfolded glycoproteins; complexes with Pdi1p, and trims a mannose from Man8GlcNac2 glycans to generate Man7GlcNac2, an oligosaccharide signal on glycoproteins destined for ER-associated protein degradation; requires Pdi1p for stability and substrate recognition; human homolog EDEM1 can complement yeast null mutant [Source:SGD;Acc:S000001247]

Chromosome VIII: 506,319-508,709 forward strand.

This transcript has 1 exon, is annotated with 16 domains and features, is associated with 48 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YHR204W Show transcript tableHide transcript table