Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; inactivates the DNA damage checkpoint; PTC2 has a paralog, PTC3, that arose from the whole genome duplication [Source:SGD;Acc:S000000891]

Chromosome V: 335,946-337,340 reverse strand.

R64-1-1:BK006939.2

This gene has 1 transcript (splice variant), 106 orthologues and 5 paralogues.

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