Protein kinase; along with its paralog, ALK1, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of cell polarity factors in mitosis, proper localization of formins and polarity factors, and survival in cells that activate spindle assembly checkpoint; phosphorylated in response to DNA damage; ALK2 has a paralog, ALK1, that arose from the whole genome duplication; similar to mammalian haspins [Source:SGD;Acc:S000000105]
Chromosome II: 207,194-209,224 forward strand.
R64-1-1:BK006936.2
This gene has 1 transcript (splice variant), 305 orthologues and 1 paralogue.