E3 ubiquitin ligase and putative helicase; involved in synthesis-dependent strand annealing-mediated homologous recombination; ensures precise end-joining along with Srs2p in the Yku70p/Yku80p/Lig4p-dependent nonhomologous end joining (NHEJ) pathway; localizes to both the mitochondrion and the nucleus; contains a Snf2/Swi2 family ATPase/helicase and a RING finger domain; interacts with Cdc48p and Smt3p; null mutant displays increased levels of spontaneous Rad52p foci [Source:SGD;Acc:S000004237]
Chromosome XII: 628,684-633,354 reverse strand.
This transcript has 1 exon, is annotated with 36 domains and features, is associated with 91 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YLR247C Show transcript tableHide transcript table