Histone acetyltransferase; critical for cell survival in presence of DNA damage during S phase, required for recovery after DSB repair; acetylates H3K56, H3K9; H3K56 acetylation activity required for expression homeostasis, buffering of mRNA synthesis rate against changes in gene dosage during S phase; involved in non-homologous end joining and regulation of Ty1 transposition; prevents hyper-amplification of rDNA; interacts physically with Vps75p [Source:SGD;Acc:S000003925]
Chromosome XII: 146,291-147,601 forward strand.
This transcript has 1 exon, is annotated with 13 domains and features, is associated with 26 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YLL002W Show transcript tableHide transcript table