Saccharomyces cerevisiae (R64-1-1)
Description

Pheromone-responsive MAPK scaffold protein; couples activation of the G-protein-coupled pheromone receptor to MAPK activation; intramolecular interaction of PH and VWA domains blocks activation of assembled signaling cascade components (Ste11p, Ste7p and Fus3p) under basal conditions; Gbeta-gamma (Ste4p-Ste18p)-dependent docking at the plasma membrane and binding of PI(4,5)P2 by the PH domain relieves autoinhibition, resulting in pheromone-dependent pathway activation [Source:SGD;Acc:S000002510]

Location
About this transcript

This transcript has 1 exon, is annotated with 16 domains and features, is associated with 60 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YDR103W Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
STE5YDR103W_mRNA2754917aaYDR103W
 
Protein coding
P32917 -Ensembl Canonical
Statistics

Exons: 1, Coding exons: 1, Transcript length: 2,754 bps, Translation length: 917 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P32917

Version

YDR103W_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD